Mäkelä HI, Kettunen MI, Gröhn OH, Kauppinen RA. Quantitative T(1rho) and magnetization transfer magnetic resonance imaging of acute cerebral ischemia in the rat. J Cereb Blood Flow Metab. 2002 May;22(5):547-58. (view details on MedLine)
Tuunanen PI, Kavec M, Jousmäki V, Usenius JP, Hari R, Salmelin R, Kauppinen RA. Comparison of BOLD fMRI and MEG characteristics to vibrotactile stimulation. Neuroimage. 2003 Aug;19(4):1778-86. (view details on MedLine)
Griffin JL, Lehtimäki KK, Valonen PK, Gröhn OH, Kettunen MI, Ylä-Herttuala S, Pitkänen A, Nicholson JK, Kauppinen RA. Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death. Cancer Res. 2003 Jun 15;63(12):3195-201. (view details on MedLine)
Lehtimäki KK, Valonen PK, Griffin JL, Väisänen TH, Gröhn OH, Kettunen MI, Vepsäläinen J, Ylä-Herttuala S, Nicholson J, Kauppinen RA. Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro. J Biol Chem. 2003 Nov 14;278(46):45915-23. Epub 2003 Sep 3. (view details on MedLine)
Kavec M, Usenius JP, Tuunanen PI, Rissanen A, Kauppinen RA. Assessment of cerebral hemodynamics and oxygen extraction using dynamic susceptibility contrast and spin echo blood oxygenation level-dependent magnetic resonance imaging: applications to carotid stenosis patients. Neuroimage. 2004 May;22(1):258-67. (view details on MedLine)
Kavec M, Gröhn OH, Gröhn HI, Garwood M, Kauppinen RA. Dynamic dephasing changes in developing ischemic cerebral infarction in rats studied by Carr-Purcell T2 magnetic resonance imaging. Magn Reson Med. 2005 Apr;53(4):960-4. (view details on MedLine)
Griffin JL, Blenkiron C, Valonen PK, Caldas C, Kauppinen RA. High-resolution magic angle spinning 1H NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma. Anal Chem. 2006 Mar 1;78(5):1546-52. (view details on MedLine)
Kettunen MI, Sierra A, Närväinen MJ, Valonen PK, Ylä-Herttuala S, Kauppinen RA, Gröhn OH. Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma. Radiology. 2007 Jun;243(3):796-803. (view details on MedLine)
Denes A, Vidyasagar R, Feng J, Narvainen J, McColl BW, Kauppinen RA, Allan SM. Proliferating resident microglia after focal cerebral ischaemia in mice. J Cereb Blood Flow Metab. 2007 Dec;27(12):1941-53. Epub 2007 Apr 18. (view details on MedLine)
Kauppinen RA, Vidyasagar R, Childs C, Balanos GM, Hiltunen Y. Assessment of human brain temperature by (1)H MRS during visual stimulation and hypercapnia. NMR Biomed. 2008 May;21(4):388-95. (view details on MedLine)
Professional Interests:
MRI and MRS techniques, Brain tumours, Cerebral haemodynamics