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Margaret A Crane-Godreau, Ph.D.
Title(s):
Research Assistant Professor of Microbiology and Immunology
Investigator - NCCC
Director - CSEAL (Cigarette Smoke Exposure Analysis Laboratory).
Department(s):
Microbiology and Immunology
Education:
UVM 1968 BS
Massachusettes College 1998 BA
Dartmouth Medical School 2004 PhD
Programs:
Immunology Program
Norris Cotton Cancer Center
Websites:
http://dms.dartmouth.edu/microbio/
http://www.cancer.dartmouth.edu/research/immunology/investigators.shtml
Contact Information:
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630 Rubin Bldg. 1 Medical Center Drive Lebanon NH 03756 |
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Phone: 603-653-9970 Email: Margaret.A.Crane |
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Selected Publications: |
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Wira CR, Grant-Tschudy KS, Crane-Godreau MA |
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Professional Interests:
Mucosal immunology, effects of cigarette smoke exposure on innate immune function.
Our lab is interested in the innate immune system at the mucosal surfaces of the female reproductive and respiratory tracts. A special focus of this work is to determine the effects of cigarette smoke on changes in immune protection. The relationship of cigarette smoke exposure to increased risk of infection is well established, however the mechanisms involved are not. Our research shows that cigarette smoke exposure reduces production of a key antimicrobial chemokine, CCL20. Ongoing research in the lab seeks to determine if similar responses to cigarette smoke exposure underlie increased rates of infection and how cigarette smoke exposure associated infection is linked to the development of cancer.
As director of the of the DMS CSEAL Dr Crane-Godreau manages the cigarette smoke exposure facility, supporting research in cancer biology, sudden infant death syndrome, cardiovascular, endocrine and immune system pathologies.
Research in our laboratory is supported by FAMRI, the Flight Attendant Medical Research Institute.
Grant Information:
FAMRI (Flight Attendant Medical Research Institute)
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