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Radu V. Stan, M.D.

Title(s):
Associate Professor of Pathology, and of Microbiology and Immunology

Department(s):
Microbiology and Immunology
Pathology

Education:
M.D. - Cluj, Romania
M.D., 1993

Dr. Stan did his postdoctoral training 1994-1999 at University of California San Diego Medical in the laboratory of George Palade, where he worked on the role of caveolae/lipid rafts and fenestrae in the cell biology of vascular permeability. He joined the faculty at UCSD as a Project Scientist (1999 ) and Research Assistant Professor (2000) in the Department of Cellular and Molecular Medicine continuing his studies of the molecular mechanisms of vascular permeability and the structures involved. In 2004, Dr. Stan joined the faculty of the departments of Pathology, and of Microbiology and Immunology at Dartmouth Medical School as an Assistant Professor.

Programs:
Angiogenesis Research Center
Program in Experimental and Molecular Medicine

Curriculum Vitae:
Stan_R_CV_2009-02-17.pdf

NIH Biosketch:
Stan_R_BIO_2009-02-17.pdf

Websites:
http://www.dartmouth.edu/~radustan/
http://myprofile.cos.com/radustan
http://www.dartmouth.edu/~angio/

Contact Information:

Dartmouth Medical School
Department of Pathology
One Medical Center Drive
Lebanon NH 03756
Office: Borwell 502W
Phone: 603-650-8781 (O),
Fax: 603-650-6120
Email: Radu.V.Stan@Dartmouth.edu


Selected Publications:

 

Murakami M, Nguyen LT, Zhuang ZW, Moodie KL, Carmeliet P, Stan RV, Simons M
The FGF system has a key role in regulating vascular integrity.
J Clin Invest 2008 Oct; 118(10):3355-66
PMID: 18776942 [PubMed - indexed for MEDLINE]

Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Buckanovich RJ, Benencia F, Stan RV, Keler T, Sarobe P, Sentman CL, Conejo-Garcia JR
Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity.
Cancer Res 2008 Sep 15; 68(18):7684-91
PMID: 18768667 [PubMed - indexed for MEDLINE]

Stan RV
Structure of caveolae.
Biochim Biophys Acta 2005 Dec 30; 1746(3):334-48
PMID: 16214243 [PubMed - indexed for MEDLINE]

Stan RV, Tkachenko E, Niesman IR
PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms.
Mol Biol Cell 2004 Aug; 15(8):3615-30
PMID: 15155804 [PubMed - indexed for MEDLINE]


Professional Interests:

Molecular mechanisms of transendothelial exchange of water and solutes (both small and large molecules) between the blood plasma and the interstitial fluid, microvascular permeability in normal and pathological state such as inflammation and cancer, angiogenesis, mechanisms of endothelial differentiation, endothelial cell biology, endocytosis, transcytosis.

Courses Taught:

General Pathology DMS I
PEMM 101
PEMM 102
PEMM 275
PEMM 126

Grant Information:

NIH, NHLBI - R01 HL83249 Cellular and molecular mechanisms of vascular permeability
NIH, NHLBI - R01 HL92085

Copyright © 2010 Trustees of Dartmouth College

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