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Paula R. Sundstrom, Ph.D.

Title(s):
Professor of Microbiology and Immunology

Department(s):
Microbiology and Immunology

Education:
University of Washington, Seattle, Washington, Ph.D., 1986
University of Washington, Seattle, Washington, M.S., 1979
B.A. Pomona College, Claremont, California, B.A., 1974
Post-doctoral Fellow, University of California, Irvine, 1989

Dr. Sundstrom joined the Department of Microbiology and Immunology in the Dartmouth Medical School in the Fall of 2003.


Programs:
Molecular Pathogenesis Program

Websites:
http://www.dartmouth.edu/~sundstrom/
http://www.dartmouth.edu/~molpath/
http://www.dartmouth.edu/~mcb/

Contact Information:

Vail Building
HB 7550 - Rm. 201
Hanover NH 03755
Office: 603-650-1613
Phone: 603-650-1629
Fax: 603-650-1318
Email: Paula.R.Sundstrom@Dartmouth.edu

Assistant: Karen L. Thompson
Asst. Phone: 603-650-1613
Asst. Email: Karen.L.Thompson@Dartmouth.edu


Selected Publications:

 

Rollenhagen C, Wollert T, Langford GM, Sundstrom P
Stimulation of cell motility and expression of late markers of differentiation in human oral keratinocytes by Candida albicans.
Cell Microbiol 2009 Jun; 11(6):946-66
PMID: 19302578 [PubMed - indexed for MEDLINE]

Wolyniak MJ, Sundstrom P
Role of actin cytoskeletal dynamics in activation of the cyclic AMP pathway and HWP1 gene expression in Candida albicans.
Eukaryot Cell 2007 Oct; 6(10):1824-40
PMID: 17715368 [PubMed - indexed for MEDLINE]

Ponniah G, Rollenhagen C, Bahn YS, Staab JF, Sundstrom P
State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1.
J Oral Pathol Med 2007 Sep; 36(8):456-67
PMID: 17686003 [PubMed - indexed for MEDLINE]

Kim S, Wolyniak MJ, Staab JF, Sundstrom P
A 368-base-pair cis-acting HWP1 promoter region, HCR, of Candida albicans confers hypha-specific gene regulation and binds architectural transcription factors Nhp6 and Gcf1p.
Eukaryot Cell 2007 Apr; 6(4):693-709
PMID: 17220463 [PubMed - indexed for MEDLINE]


Professional Interests:

Molecular mechanisms of fungal pathogenesis and prevention of fungal disease for the most common fungal pathogen of man, Candida albicans. Basic research on adherence mechanisms, signal transduction, virulence gene regulation, and host immune responses using Candida albicans as the model system are employed towards the ultimate goal of generating stratagies for improved prevention and therapy for fungal infections.

Courses Taught:

Medical Microbiology

Eukaryotic Pathogens

Grant Information:

National Institute for Craniofacial and Dental Research

National Institute for Allergy and Infectious Diseases

Burroughs Wellcome Fund

Copyright © 2009 Trustees of Dartmouth College

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