Title(s): Research Assistant Professor of Microbiology and Immunology
Department(s): Microbiology and Immunology
Education: U. London, PhD 1984 U. Auckland, BS 1972
Dr. Smith received her B.Sc. from the University of Auckland in 1973, and her Ph.D. from the University of London in 1984. After postdoctoral work as an NIH research fellow and research associate in the Department of Pediatrics at the National Jewish Center for Immunology and Respiratory Disease and the Department of Microbiology at Dartmouth Medical School, Dr. Smith joined the faculty of the Department of Microbiology at Dartmouth Medical School in 1994.
Talebian L, Coutermarsh B, Channon JY, Stanton BA Corr4A and VRT325 do not reduce the inflammatory response to P. aeruginosa in human cystic fibrosis airway epithelial cells. Cell Physiol Biochem 2009; 23(1-3):199-204 PMID: 19255514 [PubMed - indexed for MEDLINE]
Armand R, Channon JY, Kintner J, White KA, Miselis KA, Perez RP, Lewis LD The effects of ethidium bromide induced loss of mitochondrial DNA on mitochondrial phenotype and ultrastructure in a human leukemia T-cell line (MOLT-4 cells). Toxicol Appl Pharmacol 2004 Apr 1; 196(1):68-79 PMID: 15050409 [PubMed - indexed for MEDLINE]
Channon JY, Miselis KA, Minns LA, Dutta C, Kasper LH Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis. Infect Immun 2002 Nov; 70(11):6048-57 PMID: 12379681 [PubMed - indexed for MEDLINE]
Professional Interests:
Jacqueline Y. Channon Smith, Ph.D.
Research Assistant Professor of Microbiology & Immunology
The Immune Monitoring Laboratory provides blood isolation services, runs high complexity immunoassays, and carries out R&D to develop cutting edge assays. All work complies with Good Laboratory Practices standards and includes rigorous Quality Assurance and Quality Control.
My current research interest lies in understanding the immunology of Alzheimer's disease and developing a blood marker for the disease precursor, mild cognitive impairment. These studies are part of a broader investigation on a cohort of elderly people with early Alzheimer's disease, pre-Alzheimer's disease (mild cognitive impairment and cognitive complaints) and healthy controls, who are enrolled in an ongoing longitudinal neuroimaging, cognition and neurogenetics study. This work is in collaboration with Dr Andrew Saykin.