Dartmouth Medical School - Faculty Database

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Robert A. Darnall, M.D.

Title(s):
Professor of Pediatrics and of Physiology

Department(s):
Pediatrics
Physiology

Education:
Stanford University, AB 1968
U. California - Los Angeles School of Medicine, MD 1972

Programs:
Neuroscience Center at Dartmouth
Program in Experimental and Molecular Medicine

Websites:
http://dms.dartmouth.edu/ncd/

Contact Information:

Dartmouth Medical School HB 7445 Hanover NH 03755

Selected Publications:

Curran, AK, Chen, G, Darnall, RA, Filiano, JJ, Li, A, Nattie, EE. Lesion or muscimol in the rostroventrolateral medulla reduces ventilatory output and the CO₂ response in decerebrate piglets. Respir Physiol. 123:23-37, 2000.

Sun, C, Hildebrandt, L, Curran, AK, Darnall, RA, Chen, G, and Filiano, JJ. Potassium permanganate can mark the site of microdialysis in brain sections. J. Histotechnology 23:151-154. 2000.

Curran AK, Darnall RA, Filiano JJ, Li A, and Nattie EE. Muscimol dialysis in the rostral ventral medulla reduces the CO₂ response in awake and sleeping piglets. J. Appl. Physiology 90:971-980, 2001.

Professional Interests:

Dr. Darnall is the director of the training program in Neonatal-Perinatal Medicine. Dr. Darnall is especially interested in the management of the very low birthweight infant and apnea of prematurity. He is actively involved in investigation of the neurobiology of respiratory control in the neonate. Most recently he has focused on the central cardiorespiratory regulatory mechanisms involved in apnea in the new-born infant and sudden infant death syndrome. He has investigated the role of cerebral blood flow in the etiology of hypoxia induced apnea, and has studied the central mechanisms responsible for the integration of cardiovascular and respiratory activity in medullary sympathetic outflow. Currently he is investigating the integration of cardiovascular and respiratory responses to upper airway stimulation in the newborn piglet, the role of the pons in the ventilatory response to hypoxia in the piglet and newborn rat, and the influence of vestibular stimulation on sleep and breathing in the human premature infant.

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