Selected Publications
Vincenti MP and Brinckerhoff CE. Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: Can MMPs be good for you?J Cell Physiol. 213:355-364, 2007.
Blackburn JS, Rhodes CH, Coon CI and Brinckerhoff CE. RNAi inhibition of MMP-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis. Cancer Res. 67:10849-10858, 2007
Petrella BL, Lohi J and Brinckerhoff CE. Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducble factor 2alpha in von Hippel-Lindau renal cell carcinoma. Oncogene 24: 1043-1053, 2005
Wyatt CW, Geoghegan JC and Brinckerhoff CE. Short hairpin RNA mediated inhibition of Matrix Metalloproteinase-1 in MDA-231 cells: effects on matrix destruction and tumor growth .Cancer Research.65: 11101-11108, 2005
Huntington JT, Shields JM, Der CJ, Wyatt CA, Benbow U, Slingluff CL and Brinckerhoff CE. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and FGF signaling. J. Biol. Chem. 279: 33168-33176, 2004